CBEMS 219 Biomaterials: Structural Biology and Assembly (2014-2015)

CBEMS 219 Biomaterials: Structural Biology and Assembly

(Not required for any major.)
Catalog Data:

CBEMS 219 Biomaterials: Structural Biology and Assembly (Credit Units: 4) Application of fundamental concepts in structural biology (proteins, DNA/RNA, carbohydrates, lipids), biomolecular thermodynamics, and molecular interactions to the design of novel biomaterials via self-assembly. Concurrent with CBEMS 119. (Design units: 0)

Required Textbook:
. Edition, , 1969, ISBN-13 978-0138004644.

Recommended Textbook:
Relationship to Student Outcomes
No student outcomes specified.
Course Learning Outcomes. Students will:

1. Understand important molecular interactions in biology

2. Understand bioenergetics especially thermodynamics in biological systems

3. Analyze molecular architecture of living matter (nucleic acids, amino acids, carbohydrates and lipids)

4. Understand self-assembly concepts in biological systems

5. Apply self-assembly concepts in Nature to the design of novel biomaterials

Prerequisites by Topic

Thermodynamics and reaction kinetics

Lecture Topics:
  • Interactions in an aqueous environment
  • The energetics of life: thermodynamics in biological systems
  • Structure of nucleic acids
  • Proteins: primary level to protein structure
  • Protein function and evolution
  • Structure of carbohydrates
  • Structure of lipids
  • Molecular graphics and simulations
  • Self-assembly in Nature
  • Design of novel biomaterials via self-assembly
Class Schedule:

Meets for 3 hours of lecture each week for 10 weeks.

Computer Usage:

Students will use visualization and molecular simulation software

Laboratory Projects:
Professional Component
Design Content Description
Laboratory Portion:
Grading Criteria:
  • Homework: 10%
  • Midterm exam: 30%
  • Final exam: 30%
  • Research Paper: 30%
  • Total: 100%
Estimated ABET Category Content:

Mathematics and Basic Science: 0.0 credit units

Computing: 0.0 credit units

Engineering Topics: 0.0 credit units

Engineering Science: 0.0 credit units

Engineering Design: 0.0 credit units

May 27, 2014
Senate Approved:
May 8, 2014
Approved Effective:
2014 Fall Qtr