CBEMS 134 Introduction to Bioreactor Engineering (2013-2014)

CBEMS 134 Introduction to Bioreactor Engineering

(Not required for any major.)
Catalog Data:

CBEMS 134 Introduction to Bioreactor Engineering (Credit Units: 3) Unique features of bioreactors. Analyses and design of bioreactors of batch, fed-batch, and continuous flow types. Microbial reactors with and without cell recycles. Bioreactor operations for industrial-important biological products and for biological treatment of wastewater. Prerequisite: CBEMS110. Chemical Engineering majors have first consideration for enrollment. (Design units: 1.5)

Required Textbook:
None
Recommended Textbook:
None
References:

Lecture notes will be provided.

A number of books on bioreactor engineering to be assigned such as:

  • H. Scott Fogler. Elements of Chemical Reaction Engineering, 3rd Edition, Prentice Hall, 1999.

  • O. Levenspiel, Chemical Reaction Engineering, 3rd Edition, Wiley, John & Sons.

Coordinator:
Relationship to Student Outcomes
No student outcomes specified.
Course Learning Outcomes. Students will:

1. Use knowledge of advanced calculus and the maximum principles to design and analyze batch, continuous flow, and fed batch reactors.

2. Design biological reactors with cell recycle streams.

3. Apply the reactor optimization principles for the design of bioreactors for industrially important biological products, primary and secondary products.

4. Apply the reactor optimization principles for biological treatment of wastewater.

Prerequisites by Topic
  • Chemical reaction engineering concerned with the exploitation of chemical reactions on a production scale.
  • Successful design and operation of chemical reactors.
  • Chemical reactor design and analysis including qualitative arguments, simple design methods, graphical procedures, and comparison of capabilities of the major reactor types.
Lecture Topics:
  • Unique features and operational problems of bioreactors design and operation of fed-batch bioreactors and continuous flow biological reactors with and without cell recycle.
  • Recombinant cell bioreactor design and operations.
  • Pontryagin maximum principle for the determination of optimal flowrate to fedbatch reactors.
  • Optimization for the production of primary and secondary biological product.
Class Schedule:

Meets for 3 hours of lecture each week for 10 weeks.

Computer Usage:

Some homework problem requires computer solution by Matlab, Excel, Fortran.

Laboratory Projects:

None.

Professional Component

This course is designed to contribute to the student’s knowledge of biology and chemical engineering topics and biochemical reactor design.

Design Content Description
Approach:

Approach: Lecture and homework problems on design of bioreactors

Lectures: 100%
Laboratory Portion: 0%
Grading Criteria:
  • Homework 30 %
  • Mid-term 30 %
  • Final 40 %
  • Total: 100%
Estimated ABET Category Content:

Mathematics and Basic Science: 0.0 credit units

Computing: 0.0 credit units

Engineering Topics: 3.0 credit units

Engineering Science: 1.5 credit units

Engineering Design: 1.5 credit units

Prepared:
May 23, 2013
Senate Approved:
March 19, 2013
Approved Effective:
2013 Fall Qtr