BME 50A Cell and Molecular Engineering (2012-2013)

BME 50A Cell and Molecular Engineering

(Required for BME. Selected Elective for ChE and MSE.)
Catalog Data:

BME 50A Cell and Molecular Engineering (Credit Units: 4) Physiological function from a cellular, molecular, and biophysical perspective. Applications to bioengineering design. (Design units: 2)

Required Textbook:
. Edition, , 1969, ISBN-13 978-0815341291.

Recommended Textbook:
None
References:

Class notes posted on course website: http://eee.uci.edu.

Coordinator:
Elliot E. Hui
Relationship to Student Outcomes
This course relates to Student Outcomes: EAC a, EAC b, EAC c, EAC f, EAC h, EAC i, EAC j, EAC k.
Course Learning Outcomes. Students will:

1. Fundamental understanding of biochemistry and molecular biology. (EAC a)

2. Principles of experimental design, analysis, and interpretation. (EAC b)

3. Engineering and design of measurement tools for biochemistry and molecular biology. (EAC c)

4. Introductory bioethics. (EAC f)

5. Medical and economic ramifications of biotechnology. (EAC h)

6. Familiarity with relevant engineering journals and societies. (EAC i)

7. Introduction to proteomics, high-throughput screening. (EAC j)

8. Ability to solve quantitative problems related to biochemistry and molecular biology. (EAC k)

Prerequisites by Topic

Calculus, general chemistry and physics.

Lecture Topics:
  • Introduction to cells, microscopy, chemical components of cells
  • Energy, catalysis, and biosynthesis
  • Protein structure and function
  • DNA and chromosomes
  • DNA replication
  • Repair and recombination
  • From DNA to proteins
  • Control of gene expression, how genes and genomes evolve
Class Schedule:

Meets for 3 hours of lecture and 1 hour of discussion each week for 10 weeks.

Computer Usage:

Web/e-mail access

Laboratory Projects:

None.

Professional Component

Contributes toward the Biomedical Engineering Topics and Major Design experience.

Design Content Description
Approach:

Lectures cover the principles of experimental design, analysis, and interpretation; reinforced in homework. Introduction to constraint-based design in biological measurement tools.

Lectures: 100%
Laboratory Portion: 0%
Grading Criteria:
  • Homework: 30%
  • Midterm: 30%
  • Final: 40%
  • Total: 100%
Estimated ABET Category Content:

Mathematics and Basic Science: 1.5 credit units

Computing: 0.0 credit units

Engineering Topics: 2.5 credit units

Engineering Science: 0.5 credit units

Engineering Design: 2.0 credit units

Prepared:
July 9, 2012
Senate Approved:
March 5, 2002
Approved Effective:
2002 Fall Qtr