BME 50A Cell and Molecular Engineering (2011-2012)

BME 50A Cell and Molecular Engineering

(Required for BME and BMEP. Selected Elective for MSE. Elective for ChE.)
Catalog Data:

BME 50A Cell and Molecular Engineering (Credit Units: 4) Physiological function from a cellular, molecular, and biophysical perspective. Applications to bioengineering design. (Design units: 2)

Required Textbook:
. Edition, , 1969, ISBN-13 978-0815341291.

Recommended Textbook:
None
References:

Class notes posted on course website: http://eee.uci.edu.

Coordinator:
Elliot E. Hui
Relationship to Student Outcomes
This course relates to Student Outcomes: BME-a, BME-b, BME-c, BME-f, BME-h, BME-i, BME-j, BME-k.
Course Learning Outcomes. Students will:

1. Fundamental understanding of biochemistry and molecular biology. (BME-a)

2. Principles of experimental design, analysis, and interpretation. (BME-b)

3. Engineering and design of measurement tools for biochemistry and molecular biology. (BME-c)

4. Introductory bioethics. (BME-f)

5. Medical and economic ramifications of biotechnology. (BME-h)

6. Familiarity with relevant engineering journals and societies. (BME-i)

7. Introduction to proteomics, high-throughput screening. (BME-j)

8. Ability to solve quantitative problems related to biochemistry and molecular biology. (BME-k)

Prerequisites by Topic

Calculus, general chemistry and physics.

Lecture Topics:
  • Introduction to cells, microscopy, chemical components of cells
  • Energy, catalysis, and biosynthesis
  • Protein structure and function
  • DNA and chromosomes
  • DNA replication
  • Repair and recombination
  • From DNA to proteins
  • Control of gene expression, how genes and genomes evolve
Class Schedule:

Meets for 3 hours of lecture and 1 hour of discussion each week for 10 weeks.

Computer Usage:

Web/e-mail access

Laboratory Projects:

None.

Professional Component

Contributes toward the Biomedical Engineering Topics and Major Design experience.

Design Content Description
Approach:

Lectures cover the principles of experimental design, analysis, and interpretation; reinforced in homework. Introduction to constraint-based design in biological measurement tools.

Lectures: 100%
Laboratory Portion: 0%
Grading Criteria:
  • Homework: 30%
  • Midterm: 30%
  • Final: 40%
  • Total: 100%
Estimated ABET Category Content:

Mathematics and Basic Science: 1.5 credit units

Computing: 0.0 credit units

Engineering Topics: 2.5 credit units

Engineering Science: 0.5 credit units

Engineering Design: 2.0 credit units

Prepared:
May 12, 2011
Senate Approved:
March 5, 2002
Approved Effective:
2002 Fall Qtr