BME 260 Microfluidics and Lab-On-A-Chip (2016-2017)

BME 260 Microfluidics and Lab-On-A-Chip

(Not required for any major.)
Catalog Data:

BME 260 Microfluidics and Lab-On-A-Chip (Credit Units: 4) Introduction to microfluidics and state-of-the-art micro Total Analysis Systems (uTAS). Lab-on-a-Chip biomolecular assays with device design principles for microscale sample preparation, flow transport, biomolecular manipulation, separation & detection, and the technologies for integrating these devices into microsystems. Graduate students only. Concurrent with BME 147. (Design units: 0)

Required Textbook:
. Edition, , 1969, ISBN-13 978-0199235094.

Recommended Textbook:
None
References:

Class notes

Coordinator:
Abraham Lee
Relationship to Student Outcomes
No student outcomes specified.
Course Learning Outcomes. Students will:

1. Understand the fundamentals of microfluidics technology and apply it towards the manipulation and analysis of biological cells and biomolecules on biochips.

2. Be able to design a microfluidic LOC system to solve a real-world diagnostics problem.

3. Be able to compare and critique existing microfluidic systems for various biomolecular assays and develop the knowledge base in state-of-the-art microfluidic LOC devices.

4. Be able to describe the steps in constructing a microsystem (design, fabrication) for for biological sample analysis and disease management.

Prerequisites by Topic

Microfluidics device design tools, fabrication, packaging, surface treatment and testing techniques; common fabrication materials, biocompatibility, and familiarity with biomolecules and cells.

Lecture Topics:
  • Introduction: scaling of fluids at the microscale and its implications on devices
  • Review of microfabrication background
  • Physics and modeling of microfluidic systems
  • Microfluidic transport
  • Microfluidic sample preparation
  • Microfluidic sample detection
  • Two-phase microfluidics and its applications
Class Schedule:

Meets for 3 hours of lecture each week for 10 weeks.

Computer Usage:

Students will use word processors and drawing programs to do homework assignments.

Laboratory Projects:

None.

Professional Component

Contributes toward the Biomedical Engineering Topics and Major Design experience.

Design Content Description
Approach:

Specific discussions on system and device designs (50%). Students will use learned skills to design systems and devices for lab-on-chip systems (50%).

Lectures: 100%
Laboratory Portion: 0%
Grading Criteria:
  • Homework: 30%
  • Midterm: 30%
  • Final: 40%
  • Total: 100%
Estimated ABET Category Content:

Mathematics and Basic Science: 0.0 credit units

Computing: 0.0 credit units

Engineering Topics: 0.0 credit units

Engineering Science: 0.0 credit units

Engineering Design: 0.0 credit units

Prepared:
July 12, 2016
Senate Approved:
April 25, 2014
Approved Effective:
2014 Fall Qtr