BME 252 Critical Thinking in Biophotonics (2017-2018)

BME 252 Critical Thinking in Biophotonics

(Not required for any major.)
Catalog Data:

BME 252 Critical Thinking in Biophotonics (Credit Units: 2) Critical thematic review of current research papers in the field of Biophotonics. May be taken for credit 2 times. Graduate students only. (Design units: 0)

Required Textbook:
Recommended Textbook:

Materials as provided on the class website.

Vasan Venugopalan and Bruce Tromberg
Relationship to Student Outcomes
No student outcomes specified.
Course Learning Outcomes. Students will:

1. Demonstrate an in-depth knowledge of contemporary techniques, skills, and engineering tools for addressing problems in biomedicine using Biophotonic methods.

2. Res, synthesize and critically evaluate current developments in Biophotonics.

3. Work in interdisciplinary teams and orally communicate their findings and evaluations of current Biophotonics research.

Prerequisites by Topic


Lecture Topics:
  • Nonlinear Optical Microscopy of Nuclei During the Cell Cycle.
  • Biophotonics detection of field carcinogenesis.
  • Biophotonic imaging of cell migration during metastasis.
  • Frequency domain imaging of tumor microenvironment.
  • Imaging of tumor hypoxia dynamics.
  • In vivo imaging of cyanine biodistribution in cancer cells.
  • In vivo imaging of brain matastasis.
  • Bioluminescent imaging of gene therapy of breast cancer.
  • Use of Gold nanorods for photothermal tumor therapy.
Class Schedule:

Meets for 2 hours of lecture each week for 10 weeks.

Computer Usage:

Problem sets and laboratory calculations.

Laboratory Projects:


Professional Component
Design Content Description
Laboratory Portion:
Grading Criteria:
  • Presentations: 60%
  • Discussion: 40% 8 Total: 100%
Estimated ABET Category Content:

Mathematics and Basic Science: 0.0 credit units

Computing: 0.0 credit units

Engineering Topics: 0.0 credit units

Engineering Science: 0.0 credit units

Engineering Design: 0.0 credit units

February 22, 2017
Senate Approved:
April 25, 2014
Approved Effective:
2014 Fall Qtr