# BME 232 Introduction to Computational Biology (2016-2017)

#### BME 232 Introduction to Computational Biology

**BME 232 Introduction to Computational Biology (Credit Units: 4)** The use of theories and methods based on computer science, mathematics, and physics in molecular biology and biochemistry. Basics in biomolecular modeling. Analysis of sequence and structural data of biomolecules. Analysis of biomolecular functions. Graduate students only. Same as MOLBIO 223. Concurrent with BME 132, COMPSCI 183, BIO SCI M123. (Design units: 0)

Lecture material as provided on the class website.

1. This course will proved the graduate student in Biomedical Engineering with the knowledge and understanding for analyzing and simulating molecules of biomedical importance.

2. Define computational problems for biomolecules of biomedical importance. (EAC a, EAC b, EAC d)

3. Understand numerical techniques typically encountered in bimolecular research. (EAC a, EAC b)

4. Formulate solutions as algorithms. (EAC a, EAC b, EAC e)

5. Read, synthesize, and critically evaluate research in biomedical engineering.

6. Communicate effectively both orally and in writing on research issues related to biomedical engineering.

Calculus, Basic Statistics, Computer Literacy, General Chemistry, General Physics

- Biomolecular structures
- Biomolecular graphics
- Thermodynamics and molecular interactions
- Molecular mechanics
- Molecular dynamics
- Monte Carlo
- Solvation and electrostatics
- Free energy and drug design

Meets for 3 hours of lecture each week for 10 weeks.

Homework involves computer visualization and simulation tutorials.

None.

None.

- Homework: 20%
- Final Presentation: 80%
- Total: 100%

Mathematics and Basic Science: 0.0 credit units

Computing: 0.0 credit units

Engineering Topics: 0.0 credit units

Engineering Science: 0.0 credit units

Engineering Design: 0.0 credit units