BME 212 Cardiovascular Tissue Engineering (2017-2018)

BME 212 Cardiovascular Tissue Engineering

(Not required for any major.)
Catalog Data:

BME 212 Cardiovascular Tissue Engineering (Credit Units: 4) Advanced topics in biomaterials and tissue engineering with a special focus on applications in the cardiovascular system. Devices including vascular grafts and stents, heart valves, and cardiac tissue patches will be examined. Graduate students only. (Design units: 0)

Required Textbook:
Recommended Textbook:

None required. This course will utilize reading from the literature. Papers will be provided to students throughout the course.

Wendy Liu
Relationship to Student Outcomes
No student outcomes specified.
Course Learning Outcomes. Students will:

1. Apply engineering and biological principles to understand problems related to cardiovascular biomaterials tissue engineering.

2. Integrate fundamental knowledge from cell biology and biomaterials engineering to comprehend recently published approaches to cardiovascular tissue engineering.

3. Utilize knowledge gain to rationally design effective strategies for engineered cardiovascular tissue.

4. Synthesize novel ideas and strategies related to cardiovascular tissue engineering in an effort to improve current approaches.

Prerequisites by Topic

Graduate level Molecular and Cellular Engineering (BME 210) or equivalent.

Lecture Topics:
  • Overview of cardiovascular physiology & disease
  • Leukocyte adhesion and migration
  • Inflammation and foreign body response
  • Blood/biomaterials interactions
  • Biocompatibility testing
  • Materials for immunomodulation
  • Heart valves
  • Stents and vascular grafts
  • Cardiac patches
  • Extracorporeal devices
  • Regulation of medical devices
Class Schedule:

Meets for 3 hours of lecture each week for 10 weeks.

Computer Usage:

Word processing, PowerPoint.

Laboratory Projects:


Professional Component
Design Content Description
Laboratory Portion:
Grading Criteria:
  • Project: 50%
  • Presentation: 25%
  • Discussion: 25%
  • Total: 100%
Estimated ABET Category Content:

Mathematics and Basic Science: 0.0 credit units

Computing: 0.0 credit units

Engineering Topics: 0.0 credit units

Engineering Science: 0.0 credit units

Engineering Design: 0.0 credit units

February 22, 2017
Senate Approved:
April 25, 2014
Approved Effective:
2014 Fall Qtr