BME 211 Microscale Tissue Engineering (2015-2016)

BME 211 Microscale Tissue Engineering

(Not required for any major.)
Catalog Data:

BME 211 Microscale Tissue Engineering (Credit Units: 4) Engineering of physiological function at the scale of individual cells. Topics include micropatterning, microfluidic tissue culture, engineering the cellular microenvironment, and microphysiological systems. Graduate students only. (Design units: 0)

Required Textbook:
Recommended Textbook:

No textbooks required. Copies of required journal articles will be posted on EEE website for this class.

Elliot E. Hui
Relationship to Student Outcomes
No student outcomes specified.
Course Learning Outcomes. Students will:

1. Demonstrate an in-depth understanding of microtechnology tools relevant to cell culture and tissue engineering.

2. Design and interpret microscale cell biology experiments.

3. Design and communicate a research proposal utilizing the tools of microscale tissue engineering.

Prerequisites by Topic

Molecular and Cellular Engineering (BME 210)

Lecture Topics:
  • Soft lithography; microcontact printing; microfluidics
  • Cell micropatterning techniques in 2D and 3D
  • Microfluidic tissue culture
  • Engineering of cellular substrates
  • Engineering of the matrix environment
  • Engineering of soluble factor gradients
  • Engineering of the mechanical environment
  • Engineering of cell-cell interactions
  • Optogenetics
  • Microphysiological systems
Class Schedule:

Meets for 3 hours of lecture each week for 10 weeks.

Computer Usage:


Laboratory Projects:


Professional Component
Design Content Description
Laboratory Portion:
Grading Criteria:
  • Research Proposal: 40%
  • Midterm: 30%
  • Final: 30%
  • Total: 100%
Estimated ABET Category Content:

Mathematics and Basic Science: 0.0 credit units

Computing: 0.0 credit units

Engineering Topics: 0.0 credit units

Engineering Science: 0.0 credit units

Engineering Design: 0.0 credit units

April 12, 2016
Senate Approved:
November 10, 2014
Approved Effective:
2015 Fall Qtr