# BME 150 Biotransport Phenomena (2012-2013)

#### BME 150 Biotransport Phenomena

**BME 150 Biotransport Phenomena (Credit Units: 4)** Fundamentals of heat and mass transfer, similarities in the respective rate equations. Emphasis on practical application of fundamental principles. Prerequisite: Math 3D or equivalent. Only one course from BME 150, CBEMS 125C may be taken for credit. (Design units: 1)

- Truskey, G.A., Yuan, F., and Katz, D.F., Transport Phenomena In Biological Systems, Pearson Prentice Hall Bioengineering, 2nd edition, 2009, ISBN# 10-0131569880
- Incropera, F., DeWitt, D., Bergman, T., Lavine, A., Fundamentals of Heat and Mass Transfer, John Wiley & Sons, 2007, ISBN# 10-0-471-45728-0 (old or new editions acceptable)
- Fournier, R.L., Basic Transport Phenomena in Biomedical Engineering, Taylor & Francis, 2nd edition, 2006, ISBN# 10-1591690269

1. Demonstrate knowledge of the conservation of heat and mass plus the associated constitutive laws (EAC a)

2. Demonstrate knowledge of constitutive data unique to living systems including their magnitude and scale (EAC a)

3. Describe which laws and data are relevant to a specific biological system and process (EAC a)

4. Demonstrate how to apply these laws of the solution of biological problems (EAC a, EAC c, EAC h)

5. Develop/refine effective general engineering problem definition and solving skills leading to adaptive expertise (EAC a, EAC c, EAC g, EAC i, EAC j, EAC k)

6. Develop skills to disseminate information in both written and oral communications (EAC g)

Differential equations, basic programming skills (preferably in MATLAB) will be taught, but prior coursework will be very helpful

- MATLAB programming principles
- Conservation principles
- Heat transfer processes (diffusion and convection).
- One-dimensional, steady state diffusion.
- Two-dimensional, steady-state diffusion.
- Transient diffusion.
- Numerical methods to calculate diffusion fields
- External flow.
- Internal flow.
- Diffusion mass transfer.
- Physical properties of the body fluids and the cell membrane.
- Diffusion with convection.
- Conservation relations.
- Physical and flow properties of blood
- Fluid flow in circulation and tissues
- Oxygen transport
- Transport in the kidneys
- Drug transport/pharmacokinetics

Meets for 3 hours of lecture and 1 hour of discussion each week for 10 weeks.

Microsoft Excel and MATLAB for calculating solutions to assigned homework problems and challenge-based project, word processing to generate reports, student-specified software for optional presentations

None.

Contributes toward the Biomedical Engineering Topics.

Quantitative modeling of student-specified biotransport problem (100%).

- Homework: 10%
- Biotransport challenge project 40%
- Midterm: 50%
- Total: 100%

Mathematics and Basic Science: 0.0 credit units

Computing: 0.0 credit units

Engineering Topics: 4.0 credit units

Engineering Science: 3.0 credit units

Engineering Design: 1.0 credit units