BME 132 Introduction to Computational Biology (2017-2018)

BME 132 Introduction to Computational Biology

(Not required for any major.)
Catalog Data:

BME 132 Introduction to Computational Biology (Credit Units: 4) The use of theories and methods based on computer science, mathematics, and physics in molecular biology and biochemistry. Basics in biomolecular modeling. Analysis of sequence and structural data of biomolecules. Analysis of biomolecular functions. Prerequisite: MATH 2D or MATH 3A or STATS 7 or STATS 8. Same as COMPSCI 183 and BIO SCI M123. Concurrent with BME 232, MOLBIO 223. (Design units: 0)

Required Textbook:
Recommended Textbook:
Steven C. George
Relationship to Student Outcomes
No student outcomes specified.
Course Learning Outcomes. Students will:
Prerequisites by Topic


Lecture Topics:
  • Reading, assessing and presenting scientific literature
  • Basic science of cardiovascular research
  • Genetic Markers of cardiac function and maturity
  • Microenvironmental effects on cardiomyocyte function
  • Developing in vitro cardiac tissue for assessment of pathology and drug efficacy
  • Clinical cardiovascular research
  • Diagnostics for heart disease
  • Clinical treatment of heart disease
  • Cardiac clinical trials
  • Engineering tools for cardiovascular research
  • Microfluidic platforms for creating and assessing 3D cardiac tissues
  • Assessing cardiac electrophysiology in engineered cardiac tissues
  • Noninvasive optical methods of assessing cardiomyocyte function
Class Schedule:

Meets for 3 hours of lecture and 2 hours of laboratory each week for 10 weeks.

Computer Usage:


Laboratory Projects:


Professional Component
Design Content Description
Laboratory Portion:
Grading Criteria:
  • Presentations: 40%
  • Writing Assignments: 40%
  • Participation: 20%
  • Total: 100%
Estimated ABET Category Content:

Mathematics and Basic Science: 0.0 credit units

Computing: 0.0 credit units

Engineering Topics: 0.0 credit units

Engineering Science: 0.0 credit units

Engineering Design: 0.0 credit units

February 22, 2017
Senate Approved:
March 15, 2017
Approved Effective:
2017 Fall Qtr