# BME 121 Quantitative Physiology: Organ Transport Systems (2015-2016)

#### BME 121 Quantitative Physiology: Organ Transport Systems

**BME 121 Quantitative Physiology: Organ Transport Systems (Credit Units: 4)** A quantitative and systems approach to understanding physiological systems. Systems covered include the cardiopulmonary, circulatory, and renal systems. Prerequisite: BME 60B or EECS 10 or EECS 12 or ENGRCEE 20 or ENGRMAE 10 and MATH 3A and MATH 3D. Biomedical Engineering, Biomedical Engineering: Premedical majors, and Chemical Engineering have first consideration for enrollment. (Design units: 1)

- Physiology, 4e (4th Edition) ISBN: 978-0815109525
- Anatomy and Physiology (8th Edition) ISBN: 978-0073293684
- Pulmonary Physiology (5th Edition) ISBN: 978-0071345439

1. Describe and identify basic anatomical features of the pulmonary and cardiovascular systems (EAC a)

2. Describe both qualitatively and quantitatively the fundamental physiological functions of the pulmonary and cardiovascular systems. (EAC a)

3. Perform fundamental mass balances as applied to physiological systems, and solve the resulting first and second order differential equations. (EAC a)

4. Apply knowledge of anatomy and physiology of the pulmonary and cardiovascular systems together with basic engineering principles to design solutions to current medical problems. (EAC a, EAC i)

5. Formulate strategies in multidisciplinary teams to address current biomedical problems using information and resources from outside of the classroom environment. (EAC a, EAC d, EAC i)

Differential Equations

- Cardiac anatomy
- Mechanical analysis of heart Chambers, pressure flow relations
- Electrophysiological analysis of conduction in heart
- Circulatory anatomy
- Pressure flow relationships in arterial and venous trees
- Blood and blood substitutes
- Anatomy of the lungs
- Gas exchange properties of the lungs, quantitative description
- Mechanical properties of the lungs
- Respiratory Control

Meets for 3 hours of lecture and 1 hour of discussion each week for 10 weeks.

Word processing of written solutions to design problems, and basic spreadsheet calculations.

None.

Contributes toward Biomedical Engineering Topics and Major Design experience.

Small group discussion of open ended biomedical design problems (problem based learning). Written reports of design solution. (50%) Description of mathematical models which describe physiologic function and can be used in the design of solutions of pulmonary or cardiovascular problems. (50%)

- Weekly Homework: 10%
- Written reports: 25%
- Midterm exam: 25%
- Final exam: 40%
- Total: 100%

Mathematics and Basic Science: 0.0 credit units

Computing: 0.0 credit units

Engineering Topics: 4.0 credit units

Engineering Science: 3.0 credit units

Engineering Design: 1.0 credit units