BME 114 Genetic Engineering and Synthetic Biology (2017-2018)

BME 114 Genetic Engineering and Synthetic Biology

(Not required for any major. Selected Elective for BME.)
Catalog Data:

BME 114 Genetic Engineering and Synthetic Biology (Credit Units: 4) Exploring how biological functions can be engineered and synthesized from the DNA level up. Prerequisite: MATH 3D and BME 50A-B and CHEM 1C. Biomedical Engineering students have first consideration for enrollment. . (Design units: 0)

Required Textbook:
. Edition, , 1969, ISBN-13 978-0815341055.

. Edition, , 1969, ISBN-13 978-0465075706 .

Recommended Textbook:
  • Original research papers and reviews. These will all be available online through UCI's subscriptions to various scientific journals. You are responsible for downloading, printing, and reading these papers as necessary.
  • J Chris Andersons's cloning tutorial
Relationship to Student Outcomes
No student outcomes specified.
Course Learning Outcomes. Students will:
Prerequisites by Topic

Cell and Molecular Biology (BME 50A and BME 50B or equivalent), Calculus with some exposure to Differential Equations, General Chemistry, Organic Chemistry (strongly recommended but not required).

Lecture Topics:
  • Molecules of life
  • DNA technologies
  • Cloning
  • Origin of life from a synthetic biology approach
  • Genetic code manipulation
  • Genome engineering
  • Synthetic biological circuits
Class Schedule:

Meets for 3 hours of lecture each week for 10 weeks.

Computer Usage:

Requires a laptop to run free software provided

Laboratory Projects:


Professional Component
Design Content Description
Laboratory Portion:
Grading Criteria:
  • Class participation (graded on in-class literature analysis and discussion sessions, and presentation): 25%
  • Homework: 15%
  • Midterm Exam: 25%
  • Final Exam: 35%
  • Total: 100%
Estimated ABET Category Content:

Mathematics and Basic Science: 0.0 credit units

Computing: 0.0 credit units

Engineering Topics: 0.0 credit units

Engineering Science: 0.0 credit units

Engineering Design: 0.0 credit units

December 21, 2016
Senate Approved:
November 14, 2016
Approved Effective:
2017 Fall Qtr